Severe cold and snow workers, expeditions and soldiers face the same danger: frostbite or snowstorm. In which the body parts affected by the unbearable cold rot and are destroyed which have to be amputated and the affected person remains paralyzed for the rest of his life. Now a special cream can protect them from frostbite attack and limb attack.
It should be noted that in frostbite, ice penetrates the skin and melts into crystals. After that the hands become parsnips, then the sensation disappears and the skin turns black. In severe cases, the limbs have to be amputated.
A report published in the Journal of Applied Biomaterials under the American Chemical Society, published by Dr. Mania Ganguly of the Institute of Genomics and Integrative Biology in India. Mania and his colleagues have combined the chemicals that freeze cells and the dimethyl sulfoxide (DMSO) that prevents the formation of ice crystals inside cells. It contains polyvinyl alcohol (PVA) which prevents ice from freezing between cells. In this way they have made an effective ointment.
Different doses of DMSO and PVA were now tested on living cells in turn. In the laboratory, all these cells were kept in a cold environment and the cream tried to prevent them from freezing. It was found that if 2% of DMSO is mixed with 1.6 mg per ml of PVA, the best results are obtained. In other words, this technique saved the cells from ice formation and destruction with 80% success.
This ointment also protects the skin surface and other parts from freezing. The ointment has now been renamed Sin AFP. In the next step, it was mixed with aloe vera jelly and mixed on a mouse. Fifteen minutes later, the rat was placed in a very cold environment. Surprisingly, the rat survived the cold and its cells survived.
Then another rat was given cream for 30 minutes or so and it was also kept in a very cold environment but the ointment was of no use and the limbs of the rat were severely affected by the ice. It turns out that applying cream 15 minutes earlier is more beneficial.
Attempts will now be made to commercialize this anti-frostbite cream. The research was funded by the US Defense and Research Projects Agency (DARPA).
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