New York: Pancreatic cancer is spreading at an alarming rate, but now it can be reversed with a cellular ‘time machine’. It was developed by Professor Bimsu Han and his colleagues at the University of Purdue Center for Cancer Research.
“Now, for the first time, we’ve figured out a way to heal cancer cells by turning the clock back on, which could lead to new treatments and new drugs,” said Professor Ribsmo.
He first created a living model of the bubble, which he named Akins. It sends digestive juices into the small intestine. In pancreatic cancer, inflammation first develops as a result of cellular mutations, and the pancreas itself begins to be affected by its own altered enzymes.
The experts looked at the pancreatic cancer cells and asked them to make the first enzyme and thus the cells started to recover. If the cells (cells) get rid of cancer then the whole bubble can spontaneously get out of cancer which we can call reset.
To make this impossible, scientists have already worked on a cancer-resetting gene, PTF1A, which includes Professor Stephen Konizeni of the same institute. This gene is very important for the pancreas and it builds it. Now, if it is activated in the cancerous pancreas, cancer can be removed.
The experts dug a hole in a microscopic slide and filled the cells inside, which were arranged in 3D in lines. Then a brand new technology called ‘Viscus Fingering’ was developed. Then a line or cell line of cancer cells was drawn on the slide.
Now, when the PTF1A gene is reactivated in pancreatic cancer cells, the remaining cells on the slide are out of the cancerous state, that is, reprogrammed. This breakthrough could open the door to gene therapy for the treatment of pancreatic cancer.